Description

Mitochondrial haplogroup L3 is one of the most important in human prehistory: it is the direct ancestor of haplogroups M and N, which together gave rise to virtually all non-African maternal lineages. L3 is found at significant frequencies in East Africa (Ethiopia, Somalia, Kenya), and its radiation out of Africa approximately 60,000–70,000 years ago represents the matrilineal record of the Out-of-Africa migration.

Interesting Fact

Every woman outside Africa — and a significant proportion of East African women — carries a mitochondrial lineage that traces back to an L3 ancestor who lived in East Africa roughly 70,000 years ago. This makes L3 the 'mitochondrial Eve's granddaughter' of all non-African populations.

Distribution by Ethnicity

Ethnic distribution Region Frequency Sample
Somalis East Africa
30%
n=200
Ethiopians East Africa
25%
n=400
Kenyans East Africa
20%
n=300

Tags

References

  1. Behar et al. (2008) — The dawn of human matrilineal diversity. American Journal of Human Genetics 82(5), 1130–1140.
  2. Soares et al. (2012) — The expansion of mtDNA haplogroup L3 within and out of Africa. Molecular Biology and Evolution 29(3), 915–927.